There has been a great revolution in medical science over the years. Researchers and scientists vehemently contributed to the discoveries and development of pharmaceutical compounds since the early 20th century. Benzodiazepine drug class, which was once considered a family of hypnotic agents also went through the evolutionary process of pharmaceutical science. Later, using some of the traits of this drug class and combining them with other molecularly different compounds, a new family of drugs by the name of Non-benzodiazepine or simply known as “Z Class of Drugs” was formed. In recent years, especially sleeping pills which belonged to the benzo category have been widely replaced by the new age sleeping tablets that are categorized as Z Drugs. We can’t simply conclude which one is better if we compare benzodiazepines vs Z drugs. Therefore, we have attempted to compress an easy-to-understand comparison between these two families of drugs.
About Benzodiazepine Sleeping Pills
The scientific name Benzodiazepine was first used in the year 1955 when a scientist named Leo Sternbach discovered a compound called chlordiazepoxide (Librium). Subsequently, the medicinal compound showed some remarkable hypnotic property. Gradually, on getting accepted by the medical associations, the Librium along with some other medical products got enlisted in the category of Benzodiazepine drugs. Additionally, these medicines were minor tranquilisers and doctors around the world highly prescribed such drugs for treating sleep issues and anxiety-related problems. Mostly all sedatives from this drug class consisted of anxiolytic and hypnotic problems.
Working Mechanism Of Benzodiazepine Sleeping Pills
The working mechanism of most benzos involves the interaction of the active molecules of the medicinal compound with the GABA receptors of the nervous system. Consequently, this interaction causes a slowdown in the transmission of stress signals and entices the Central Nervous System to go to a docile state. Usually, an individual who ingests these benzodiazepine sleeping pills or anxiety medicine gets quick relief with a short onset.
List Of Common Benzodiazepine Sleeping Pills & Anxiety Medicines
Benefits Of Benzodiazepines:
- They have faster Onset
- Relatively Cheaper Than Z Drugs
- Easily Available
- Equally effective on insomnia and anxiety
Harms Of Benzodiazepines:
- Chances of Withdrawal Symptoms
- Can lead to dependency
- Noticeable Side-effects
About Non-Benzodiazepine Sleeping Pills
Non-benzodiazepine is a successor class of benzodiazepines. Sleeping pills and anxiety drugs under this class have slightly different properties than the benzos. Noticing the side-effects caused by the benzodiazepines, scientists further developed the medical compounds which led to the discovery of safe sleeping pills and anxiety medications that involved lesser risks. In the present scenario, most of the medical practitioners prescribe medicines from this specific class for the treatment of diseases like insomnia, hypersomnia and anxiety disorder.
Working Mechanism Of Z Drugs
The active molecules of the hypnotic compounds interact with the GABA receptors quite similar to as the benzo drugs’ molecules would do. But, the Z drugs would only target the selective choice of receptors i.e. targeting only alpha subunits only. Also, the refined impact of the drug doesn’t tamper with the functioning of the other receptors of the nervous system that are not responsible for the transmission of sleep signals and stress signals.
List Of Z Drugs Available
Sleeping pills in UK & US from this class of drugs are easily available these days. Moreover, people find it satisfactory that they can buy non-benzodiazepine sleeping pills online from most of the e-pharmacies without much hassle. Following is the list of some of the most common sleeping pills from the “Z” category of drugs:
From the aforementioned concise list of Z drugs, there is a great demand for generic zopiclone in UK due to its remarkable treating effect on insomnia. Generally, seekers buy zopiclone online in UK from online pharmacies. Additionally, the sales figure of this medicine has rocketed over the span of the last 3 years.
Benefits Of Z Drugs
- Low addiction chances
- Easily Available Over-the-Counter
- Prolonged effect on ailments
- Available in economical generic form
Harms Of Z Drugs
- Users may develop tolerance
- Reported mild side-effects
- Chances of contraindications with many compounds